群馬大学HP 群馬大学医学部医学科HP






現在、公衆衛生学教室で取り組んでいる研究課題は、以下のように多岐にわたっています。
 
  微量元素の栄養疫学的研究 
  セレン蛋白の分析化学的研究 
  セレンとカドミウムの相互作用機構の解明 
  小児アレルギー疫学研究 
  こもいせ研究(中高年者のコホート研究.死亡・罹病への心理社会的リスク要因の検討) 
  保健医療情報データベース解析 
  自殺予防のためのうつスクリーニング調査(群馬県との共同研究) 
8   学校児童のメンタルヘルスの現状評価と改善策の提案 
  セレン強化スプラウトの開発 
10    疫学統計および数理モデルによる感染症流行と感染伝播の評価
11    労働者の精神的および身体的健康に影響する環境因子の解明 
12    人工知能(AI)の深層学習(Deep Learning)技術を応用した労働安全衛生手法の開発 
     
本教室における最近の業績は以下の通りです。   
 
論文など 
2021  
・    Uchida M. Changes in numbers of COVID-19 cases among residents of sightseeing resort areas before and during the “Go To Travel” campaign: Descriptive epidemiology in Gunma Prefecture. Japanese Journal of Infectious Diseases (in press). (Link)
2020  
・     Herawati N, Suzuki S, Koyama H, Hayashi K. Smoking has physical and psychoactive effects, and heavy smoking is associated with depression. Japan J Health Hum Ecol. 2020 86(6):273-280. (Link)
・     Pratiwi R, Shalihat A, Dewantisari D, Nafisah RA, Yunita, Saputri FA, Gozali D, Pamungkas K, Lesmana R, Koyama H, Mutakin. Correlation study between gastronomy culture and content of selenium towards prevalence of cardiovascular and diabetes in West Java, Indonesia. J Trace Elem Med Biol. 2020 Nov 13;64:126679. (Link) 
・    Handa E, Puspitasari IM, Abdulah R, Yamazaki C, Kameo S, Nakano T, et al. Recent advances in clinical studies of selenium supplementation in radiotherapy. J Trace Elem Med Biol. 2020 62:126653. (Link)
・    小山 洋. セレンの基礎・臨床でのupdate. 細胞 2020 52(3):20-23.(Link) 
・    調 憲, 播本憲史, 小山 洋. 都道府県ごとの新型コロナウイルス(COVID-19)累積感染割合と人口密集度の指標との関連に関する研究. 北関東医学 2020 70(3):235-242. (Link)
・    Erdenee O, Tumejargal A, Parchaa T, Yamazaki C, Koyama H. Distribution of midwives in Mongolia: A secondary data analysis. Midwifery. 2020 86:102704. (Link)
・    Paramita SA, Yamazaki C, Koyama H. Determinants of life expectancy and clustering of provinces to improve life expectancy: an ecological study in Indonesia. BMC Public Health. 2020 20:351. (Link)
・    Puspitasari IM, Yusuf L, Sinuraya RK, Abdulah R, Koyama H. Knowledge, Attitude, and Practice During the COVID-19 Pandemic: A Review. Journal of Multidisciplinary Healthcare. 2020 13:727-33. (Link)
・    Yamazaki C, Goto A, Iwasaki M, Sawada N, Oba S, Noda M, Iso H, Koyama H, Tsugane S. Body mass index and mortality among middle-aged Japanese individuals with diagnosed diabetes: The Japan Public Health Center-based prospective study (JPHC study). Diabetes Res Clin Pract. 2020 164:108198. (Link)
・    Sekiguchi A, Inoue Y, Yamazaki S, Uchiyama S, Ishikawa O, Kuribayashi S, Uraoka T, Hara K, Yamaguchi K, Maeno T, Uchida M, Koyama H, Motegi S. Prevalence and clinical characteristics of earlobe crease in systemic sclerosis: Possible association with vascular dysfunction. J Dermatol. 2020 47(8):870-875.(Link)
・    Uchida M, Takeuchi S, Saito M, Koyama H. Effects of influenza vaccination on seasonal influenza symptoms: a prospective observational study in elementary schoolchildren in Japan. Heliyon. 2020 6(2):e03385. (Link) 
・     内田満夫. 新型コロナウイルス感染症から学ぶ〜感染拡大の評価と予測. 小児科臨床. 2020 73(12):1639-1643. (Link)
・    内田満夫,筒井保博,野下浩司,小山 洋. 学習型AIを用いた労働者の健康診断結果の予測:ある企業の労働者におけるパイロット研究. 産業衛生学雑誌. 2020 (in press) (Link) 
2019  
・    齋藤貴之, 岸 美紀子, 鯉淵典之, 小山 洋, 坂本雅昭, 石崎泰樹. 群馬大学医学部における学生国際交流. 2019 69(3):263-265. (Link)
・    Li Y, Suzuki S, Wakimoto Y, Hayashi K, Koyama H. Household Income and Mortality Risk Related to Different Sociodemographic Characteristics of Japanese Men from a Cohort Study. Japan J Health Hum Ecol. 2019 85(3)108-120. (Link)
・    Todokoro D, Kamei S, Goto H, Ikeda Y, Koyama H, Akiyama H. Acute retinal necrosis following herpes simplex encephalitis: a nationwide survey in Japan. Jpn J Ophthalmol. 2019 63(4):304-309. (Link)
・    Kartamihardja AAP, Hanaoka H, Andriana P, Kameo S, Takahashi A, Koyama H, et al. Quantitative analysis of Gd in the protein content of the brain following single injection of gadolinium-based contrast agents (GBCAs) by size exclusion chromatography. British J Radiol. 2019 92(1099):20190062. (Link)
・    Murayama Y, Inoue K, Yamazaki C, Kameo S, Nakazawa M, Koyama H. Association between Depressive State and Lifestyle Factors among Residents in a Rural Area in Japan: A Cross-Sectional Study. Tohoku J Exp Med. 2019 249(2):101-111. (Link) 
・    内田満夫,野下浩司,浅尾高行,小山 洋. 社会医学領域において進めるAI研究. Precision Medicine. 2019 2(12):72-76. (Link)  
・    内田満夫,野下浩司,小山 洋. VDT作業者の安全衛生評価におけるDeep Learningの活用. 産業衛生学雑誌. 2019 61(6):256-260. (Link) 
・    内田満夫,野下浩司,渡辺由佳子,小山 洋. 社会医学におけるAI研究. 細胞 2019 51(7):42-45. (Link)  
・  Erdenee O, Narula IS, Yamazaki C, Kameo S, Koyama H. Mongolian Health Sector Strategic Master Plan (2006-2015): A foundation for achieving universal health coverage. Int J Health Plann Manage. 2019 34(1):e314-e326. (Link)  
・     Endo A, Uchida M, Kucharski AJ, Funk S. Fine-scale family structure shapes influenza transmission risk in households: Insights from primary schools in Matsumoto city, 2014/15. PLoS Comput Biol. 2019 15(12) e1007589 (Link) 
・    Uchida M. Longitudinal epidemiological studies to clarify the difference in effectiveness of countermeasures against influenza in different age groups. Impact. 2019 2019(4):82-84. (Link
・    内田満夫,野下浩司,渡辺由佳子,小山 洋. 社会医学におけるAI研究. BIO Clinica 2019 34(3):89-93. (Link) 
2018  
内田満夫,野下浩司,筒井保博,小山 洋. 産業保健におけるDeep Learningの活用:物流企業の職場巡視画像を用いたパイロット研究. 産業衛生学雑誌. 2018 60(6):191-195.(Link)  
・    Uchida M. Individual background factors associated with vaccination for seasonal influenza in Japanese schoolchildren. J Infect Chemother. 2018 24(1):36-39.(Link) 
・    Uchida M, Morita H. Association between long work hours and depressive state: a pilot study of propensity score matched Japanese white-collar workers. Ind Health. 2018 56(3):207-211. (Link) 
・    Uchida M, Kaneko M, Hidaka Y, Yamamoto H, Honda T, Takeuchi S, Saito M, Kawa S. High vaccination coverage is associated with low epidemic level of seasonal influenza in elementary schools: an observational study in Matsumoto City, Japan. BMC Infect Dis. 2018 18(1):128. (Link) 
・    Saputri FA, Kang D, Kusuma ASW, Rusdiana T, Hasanah AN, Mutakin, Surono IS, Koyama H, Abdulah R. Lactobacillus plantarum IS-10506 probiotic administration increases amlodipine absorption in a rabbit model. J Int Med Res. 2018 300060518788994. (Link)
・  Iijima H, Suzuki S, Koyama H, Nakazawa M, Wakimoto Y. Agricultural workers in a cohort of middle-aged Japanese women showed better health status than did women with other occupations. J Rural Med. 2018 13(1):57-63. (Link) 
・  Paramita SA, Yamazaki C, Setiawati EP, Koyama H. Distribution trends of Indonesia's health care resources in the decentralization era. Int J Health Plann Manage. 2018 33(2):e586-e596. (Link)   
・    Febiyanto N, Yamazaki C, Kameo S, Sari DK, Puspitasari IM, Sunjaya DK, Herawati DMD, Nugraha GI, Fukuda T, Koyama H. Effects of Selenium Supplementation on the Diabetic Condition Depend on the Baseline Selenium Status in KKAy Mice. Biol Trace Elem Res. 2018 181(1):71-81. (Link) 
・    Anneke Rosma, Chiho Yamazaki, Satomi Kameo, Dewi M. Herawati, Rovina Ruslami, Ardini Raksanagara, Hiroshi Koyama. Factors Influencing Private Practitioners to Report Tuberculosis Cases. Pharmacology and Clinical Pharmacy Research Vol 1, No 1: 1-10, 2018. (Link)
2017  
・    Erdene K, Nakajima T, Kameo S, Khairinisa MA, Lamid-Ochir O, Tumenjargal A, Koibuchi N, Koyama H, Tsushima Y. Organ retention of gadolinium in mother and pup mice: effect of pregnancy and type of gadolinium-based contrast agents. Jpn J Radiol. 2017 35(10):568-573. (Link)
・    Erdenee O, Paramita SA, Yamazaki C, Koyama H. Distribution of health care resources in Mongolia using the Gini coefficient. Hum Resour Health. 2017 15(1):56. (Link)
・    Abdulah R, Suradji EW, Subarnas A, Supratman U, Sugijanto M, Diantini A, Lestari K, Barliana MI, Kawazu S, Koyama H. Catechin Isolated from Garcinia celebica Leaves Inhibit Plasmodium falciparum Growth through the Induction of Oxidative Stress. Pharmacogn Mag. 2017 13(Suppl 2):S301-S305. (Link)
・    Puspitasari IM, Yamazaki C, Abdulah R, Putri M, Kameo S, Nakano T, Koyama H. Protective effects of sodium selenite supplementation against irradiation-induced damage in non-cancerous human esophageal cells. Oncol Lett. 2017 13(1):449-454. (Link)
・    Oyanagi T, Takizawa T, Aizawa A, Solongo O, Yagi H, Nishida Y, Koyama H, Saitoh A, Arakawa H. Suppression of MUC5AC expression in human bronchial epithelial cells by interferon-γ. Allergol Int. 2017 66(1):75-82. (Link)
2016  
・    Kartamihardja AA, Nakajima T, Kameo S, Koyama H, Tsushima Y. Impact of Impaired Renal Function on Gadolinium Retention After Administration of Gadolinium-Based Contrast Agents in a Mouse Model. Invest Radiol. 2016 51(10):655-60. (Link)
・    Kartamihardja AA, Nakajima T, Kameo S, Koyama H, Tsushima Y. Distribution and clearance of retained gadolinium in the brain: differences between linear and macrocyclic gadolinium based contrast agents in a mouse model. Br J Radiol. 2016 89(1066):20160509. (Link)
・    Ariyani W, Iwasaki T, Miyazaki W, Khongorzul E, Nakajima T, Kameo S, Koyama H, Tsushima Y, Koibuchi N. Effects of Gadolinium-Based Contrast Agents on Thyroid Hormone Receptor Action and Thyroid Hormone-Induced Cerebellar Purkinje Cell Morphogenesis. Front Endocrinol (Lausanne). 2016 7:115.  (Link)
・    Mutakin, Rivai IF, Setiawan A, Abdulah R, Kobayashi K, Yamazaki C, Kameo S, Nakazawa M, Koyama H. A STUDY OF THE ASSOCIATION BETWEEN SELENIUM AND CARDIOVASCULAR DISEASE IN LAMPUNG, INDONESIA. Southeast Asian J Trop Med Public Health. 2016 47(2):299-308. (Link)
・    Subarnas A, Diantini A, Abdulah R, Zuhrotun A, Nugraha PA, Hadisaputri YE, Puspitasari IM, Yamazaki C, Kuwano H, Koyama H. Apoptosis-mediated antiproliferative activity of friedolanostane triterpenoid isolated from the leaves of Garcinia celebica against MCF-7 human breast cancer cell lines. Biomed Rep. 2016 Jan;4(1):79-82. Epub 2015 . (Link)
・    Nazri C, Yamazaki C, Kameo S, Herawati DMD, Sekarwana N, Raksanagara A, Koyama H. Factors influencing mother's participation in Posyandu for improving nutritional status of children under-five in Aceh Utara district, Aceh province, Indonesia. BMC Public Health. 2016 16:69. (Link)
 
著書,指針など   
・    セレン欠乏症の診療指針2018. 児玉浩子, 浅桐公男, 恵谷ゆり, 小山 洋, ゙ 英樹, 位田 忍, 田中芳明, 高柳正樹, 船越政史, 吉田宗弘. 日本臨床栄養学会雑誌 2018 40(4):239-283. (Link) 
     
上記の論文について詳細を知りたい方,また研究内容に興味をお持ちの方は,お気軽に教室までご連絡ください。研究グループへの参加,また共同研究も歓迎いたします。   


 


 

群馬大学 大学院医学系研究科 公衆衛生学分野 
〒371-8511 前橋市昭和町3-39-22 基礎医学棟5階: Phone: 027-220-8013 / FAX: 027-220-8016